Formulation: A solid
Formal Name: 4-methyl-1,2-benzenediol
Purity: ≥98%
Formula Markup: C7H8O2
Formula Weight: 124,1
Shelf life (days): 1460
CAS Number: 452-86-8
Notes: 4-Methylcatechol is a methylcatechol with diverse biological activities and an active metabolite of the flavonoid quercetin (Item No. 10005169).{67269,67270,67271} It is formed from quercetin by gut microbiota.{67269} 4-Methylcatechol inhibits migration of, and induces cell cycle arrest in the G2/M phase, production of reactive oxygen species (ROS), and apoptosis in, 1205Lu melanoma cells when used at concentrations of 10 and 25 µg/ml.{67270} It induces relaxation of isolated rat aortic rings and mesenteric arteries (EC50s = 49.1 and 21.2 µM, respectively) and reduces blood pressure in spontaneously hypertensive stroke-prone (SHRSP) rats.{67271}