4-Methylcatechol, CAS 452-86-8

4-Methylcatechol, CAS 452-86-8
SKU
CAY36429-50
Packaging Unit
50 g
Manufacturer
Cayman Chemical

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Formulation: A solid

Formal Name: 4-methyl-1,2-benzenediol

Purity: ≥98%

Formula Markup: C7H8O2

Formula Weight: 124,1

Shelf life (days): 1460

CAS Number: 452-86-8

Notes: 4-Methylcatechol is a methylcatechol with diverse biological activities and an active metabolite of the flavonoid quercetin (Item No. 10005169).{67269,67270,67271} It is formed from quercetin by gut microbiota.{67269} 4-Methylcatechol inhibits migration of, and induces cell cycle arrest in the G2/M phase, production of reactive oxygen species (ROS), and apoptosis in, 1205Lu melanoma cells when used at concentrations of 10 and 25 µg/ml.{67270} It induces relaxation of isolated rat aortic rings and mesenteric arteries (EC50s = 49.1 and 21.2 µM, respectively) and reduces blood pressure in spontaneously hypertensive stroke-prone (SHRSP) rats.{67271}
More Information
SKU CAY36429-50
Manufacturer Cayman Chemical
Manufacturer SKU 36429-50
Green Labware No
Package Unit 50 g
Quantity Unit STK
Application Reinstoffe
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