4-oxo Docosahexaenoic Acid, CAS 845673-74-7

Formulation: A solution in ethanol

Formal Name: 4-oxo-5E,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid

Purity: ≥90%

Formula Markup: C22H30O3

Formula Weight: 342,5

Shelf life (days): 365

CAS Number: 845673-74-7

Notes: 4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA (Item No. 90310) with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 µM, however it increased proliferation of MCF-7 cells.{34687} 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 µM.{16872}

• SKU: CAY21373-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21373-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK