Formulation: A crystalline solid
Formal Name: cholest-5-ene-3β,4β-diol
Purity: ≥95%
Formula Markup: C27H46O2
Formula Weight: 402,7
Shelf life (days): 730
CAS Number: 17320-10-4
Notes: 4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation.{31450} It is formed from cholesterol by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5.{31450} 4β-hydroxy Cholesterol has an unusually long half-life in plasma (~60 hours) as a result of slow elimination, particularly due to a slow rate of 7α-hydroxylation, which is the rate-limiting step for further conversion into bile acids.