(±)5-HEPE, CAS 83952-40-3

(±)5-HEPE, CAS 83952-40-3
SKU
CAY32200-50
Packaging Unit
50 µg
Manufacturer
Cayman Chemical

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Formulation: A solution in ethanol

Formal Name: (±)-5-hydroxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic acid

Purity: ≥97%

Formula Markup: C20H30O3

Formula Weight: 318,5

Shelf life (days): 365

CAS Number: 83952-40-3

Notes: (±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5.{11149,11166,11167} The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.{11167}
More Information
SKU CAY32200-50
Manufacturer Cayman Chemical
Manufacturer SKU 32200-50
Green Labware No
Package Unit 50 µg
Quantity Unit STK
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