5α,6α-epoxy Cholestanol, CAS 1250-95-9

Formulation: A crystalline solid

Formal Name: (3β,5α,6α)-5,6-epoxy-cholestan-3-ol

Purity: ≥95%

Formula Markup: C27H46O2

Formula Weight: 402,7

Shelf life (days): 1460

CAS Number: 1250-95-9

Notes: 5α,6α-epoxy Cholestanol is an oxysterol and a metabolite of cholesterol produced by oxidation.{45075} 5α,6α-epoxy Cholestanol accumulates in MCF-7 breast cancer cells in a reactive oxygen species-dependent manner following tamoxifen and PBPE application and induces triacylglycerol biosynthesis by binding to liver x receptor β (LXRβ).{45076} 5α,6α-epoxy Cholestanol levels are increased in rat aorta and mesenteric artery following orchidectomy, an effect that can be prevented by a DHA-supplemented diet.{45075} Levels are also increased in post-mortem frontal and occipital cortex of patients with Alzheimer’s disease.{45077}

• SKU: CAY25539-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 25539-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK