Formulation: A crystalline solid
Formal Name: 21-(3-carboxy-1-oxopropoxy)-11β,17-dihydroxy-6α-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥98%
Formula Markup: C26H34O8
Formula Weight: 474,6
Shelf life (days): 1460
CAS Number: 2921-57-5
Notes: 6α-Methylprednisolone 21-hemisuccinate is a prodrug form of the synthetic glucocorticoid methylprednisolone (Item No. 15013).{21229} It is converted to methylprednisolone by carboxylesterase 2 (CES2).{65360} Nanoliposomes containing 6α-methylprednisolone 21-hemisuccinate decreases disease severity in a rat model of adjuvant-induced arthritis.{65361} Formulations containing 6α-methylprednisolone 21-hemisuccinate have been used as anti-inflammatory agents and immunosuppressants with indications in allergic reactions and dermatologic, renal, gastrointestinal, respiratory, and ophthalmic diseases, as well as endocrine, hematologic, and rheumatic disorders.
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