Formulation: A crystalline solid
Formal Name: 6S,9α-epoxy-11α,15S-dihydroxy-prost-13E-en-1-oic acid
Purity: ≥99%
Formula Markup: C20H34O5
Formula Weight: 354,5
Shelf life (days): 730
CAS Number: 62770-50-7
Notes: 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 µM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.{509,1926}