8-dehydro Cholesterol, CAS 70741-38-7

Formulation: A solid

Formal Name: cholesta-5,8-dien-3β-ol

Purity: ≥90%

Formula Markup: C27H44O

Formula Weight: 384,6

Shelf life (days): 730

CAS Number: 70741-38-7

Notes: 8-dehydro Cholesterol (8-DHC) is an isomer of the cholesterol precursor 7-DHC (Item No. 14612).{36903,36904,35287} It accumulates in tissues and plasma in patients with Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in DHCR7, the gene encoding 3β-hydroxysterol-Δ7-reductase, and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features. 8-DHC levels are increased in serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{36903}

• SKU: CAY25970-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 25970-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK