8-iso Prostaglandin E2, CAS 27415-25-4

Formulation: A crystalline solid

Formal Name: (8β)-11α,15S-dihydroxy-9-oxo-prosta-5Z,13E-dien-1-oic acid

Purity: ≥99%

Formula Markup: C20H32O5

Formula Weight: 352,5

Shelf life (days): 730

CAS Number: 27415-25-4

Notes: 8-iso Prostaglandin E2 (8-iso PGE2) is one of several isoprostanes produced from arachidonic acid during lipid peroxidation.{1943} It is a potent renal vasoconstrictor in the rat.{1943,5157} 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 µM, respectively.{1258} When infused into the renal artery of the rat at a concentration of 4 µg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.{1943}

• SKU: CAY14350-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 14350-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK