Formulation: A crystalline solid
Formal Name: 9-methylene-11α,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid, monopotassium salt
Purity: ≥98%
Formula Markup: C23H37O4 • K
Formula Weight: 416,6
Shelf life (days): 180
CAS Number: 122576-55-0
Notes: 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (metenprost) is a potent analog of PGE2 with an extended half-life in vivo. In combination with various other PG derivatives, metenprost results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of metenprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy.{4692} This PG mixture is ineffective on monkeys in their third trimester of pregnancy.{4692} Metenprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.{4692,464}
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