Formulation: A solution in methyl acetate
Formal Name: 9-[[(9Z)-1-oxo-9-hexadecen-1-yl]oxy]-octadecanoic acid
Purity: ≥95%
Formula Markup: C34H64O4
Formula Weight: 536,9
Shelf life (days): 365
CAS Number: 1481636-43-4
Notes: Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity in mice.{27644} Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 9-POHSA is a FAHFA consisting of palmitoleic acid esterified at the 9-position of hydroxy stearic acid. The levels of POHSA are significantly elevated in serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.{27644} As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 9-POHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.{27644}
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