Formulation: A crystalline solid
Formal Name: (3α,5β,6β,7α)-3,6,7-trihydroxy-cholan-24-oic-2,2,4,4-d4 acid
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C24H36D4O5
Formula Weight: 412,6
Shelf life (days): 730
Notes: α-Muricholic acid-d4 is intended for use as an internal standard for the quantification of α-muricholic acid (Item No. 20291) by GC- or LC-MS. α-Muricholic acid is a murine-specific primary bile acid.{30824,30558} Dietary administration of soybean protein decreases fecal levels of α-muricholic acid in mice with high-fat diet-induced obesity, which correlates with increases in fecal Clostridium cluster XIVa, a major producer of secondary bile acids.{42723} Plasma, liver, and muscle levels of α-muricholic acid are increased in mice switched from a high-fat to low-fat diet.{42724}