Formulation: A solid
Formal Name: 2R-(acetyl-d3-oxy)-3-carboxy-N,N,N-trimethyl-1-propanaminium, monochloride
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C9H15D3NO4 • Cl
Formula Weight: 242,7
Shelf life (days): 730
CAS Number: 362049-62-5
Notes: Acetyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of L-acetylcarnitine (Item No. 16948) by GC- or LC-MS. Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine (Item No. 21489) that is catabolized by plasma esterases into carnitine.{27352,27356,27355} Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund's adjuvant.{43555}
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