Formulation: A solid
Formal Name: (8α,9β,14β)-11β,23S,24R,25-tetrahydroxy-dammar-13(17)-en-3-one
Purity: ≥98%
Formula Markup: C30H50O5
Formula Weight: 490,7
Shelf life (days): 1460
CAS Number: 19885-10-0
Notes: Alisol A is a terpenoid that has been found in A. orientale and has diverse biological activities.{58513,58514,58515,58516} It inhibits the secretion of hepatitis B virus (HBV) surface antigen in HBV-infected 2.2.15 cells (IC50 = 39 µM).{58514} Alisol A (20 and 40 µM) induces cell cycle arrest at the G0/G1 phase and autophagy in MDA-MB-231 human breast cancer cells.{58515} It reduces hepatic steatosis and increases in plasma triglyceride, total cholesterol, LDL-C, and HDL-C levels in a mouse model of high-fat diet-induced obesity when administered at a dose of 100 mg/kg per day.{58516} Alisol A decreases blood glucose and insulin levels in intraperitoneal glucose and insulin tolerance tests, respectively, in the same model.
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