Formulation: A solution in methanol
Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenoic-1,2,3,4,5-13C5 acid
Purity: ≥95%
Formula Markup: C15[13C]5H32O2
Formula Weight: 309,4
Shelf life (days): 365
Notes: Arachidonic acid (Item No. 90010) is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.{3656} Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.{314} Arachidonic acid 1,2,3,4,5-13C is an isotopically enriched form of this PUFA with carbon-13 occurring at positions 1, 2, 3, 4, and 5. It can be used to study metabolic processes related to arachidonic acid by means of mass spectrometry.
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