Formulation: A solution in methyl acetate
Formal Name: N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide
Purity: ≥98%
Formula Markup: C30H42N2O2
Formula Weight: 462,7
Shelf life (days): 730
CAS Number: 187947-37-1
Notes: Arachidonoyl serotonin is an inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for inactivation of anandamide and other endogenous cannabinoids. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 µM. Both the Km and the Vmax of the enzyme are affected, indicating the Arachidonoyl serotonin is a very tight binding, competitive inhibitor of FAAH. Arachidonoyl serotonin does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity.{6644}