Bavachalcone, CAS 28448-85-3

Formulation: A solid

Formal Name: (2E)-1-[2,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

Purity: ≥98%

Formula Markup: C20H20O4

Formula Weight: 324,4

Shelf life (days): 1460

CAS Number: 28448-85-3

Notes: Bavachalcone is a polyketide synthase-derived chalcone and flavonoid that has been found in P. corylifolia and has diverse biological activities.{61669,61670,61671,61672,61673} It inhibits α-glucosidase and the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT1A7 (IC50s = 11.1, 11.3, and 3.6 µM, respectively).{61670,61671} Bavachalcone is cytotoxic to K562 chronic myeloid leukemia cells (IC50 = 2.77 µM).{61672} It inhibits RANKL-induced osteoclastogenesis of isolated mouse bone marrow-derived macrophages (BMDMs) when used at a concentration of 5 µg/ml.{61673}

• SKU: CAY34673-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34673-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK