Formulation: A crystalline solid
Formal Name: ergosta-5,22E-dien-3β-ol
Purity: ≥95%
Formula Markup: C28H46O
Formula Weight: 398,7
Shelf life (days): 1460
CAS Number: 474-67-9
Notes: Brassicasterol is a phytosterol found in canola and rapeseed oils, marine algae, and shellfish.{38219} It inhibits recombinant sterol Δ24-reductase with a Ki value of 42.7 μM in vitro. Brassicasterol increases accumulation of desmosterol, a cholesterol precursor and substrate of sterol Δ24-reductase, and inhibits cholesterol formation in HL-60 cells in a dose-dependent manner. It also inhibits the hemolytic activity of pneumolysin from S. pneumoniae without affecting bacterial growth at concentrations up to 1,000 μg/ml.{38220}