C12 Ceramide (d18:1/12:0), CAS 74713-60-3

Formulation: A crystalline solid

Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-dodecanamide

Purity: ≥98%

Formula Markup: C30H59NO3

Formula Weight: 481,8

Shelf life (days): 1460

CAS Number: 74713-60-3

Notes: C12 ceramide is a naturally occurring ceramide that is formed when C12 sphingomyelin is hydrolyzed by acid sphingomyelinase (ASM).{38210} It is a substrate for acid ceramidase, an enzyme that has 2- to 12-fold higher activity in fibroblasts from patients with Farber disease, a lipid storage disorder.{38209} C12 ceramide is found in the Wharton's jelly, a protective coating that surrounds umbilical cord vessels, of babies born to women with pre-eclampsia.{38208} BODIPY C12 ceramide has been used to assess levels of ASM activity in plasma of patients with type A or B Niemann-Pick disease.{38210}

• SKU: CAY22530-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22530-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK