Formulation: A crystalline solid
Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-tetradecanamide
Purity: ≥95%
Formula Markup: C32H63NO3
Formula Weight: 509,9
Shelf life (days): 730
CAS Number: 34227-72-0
Notes: C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6.{35051} During nutrient-deprivation-induced necroptosis in MEF cells, C14 ceramide levels increase in a time-dependent manner.{35053} C14 ceramide plasma levels were reduced in obese patients with or without diabetes following a 12-week supervised exercise training program, correlating positively with weight and fat loss and negatively with an increase in insulin sensitivity.{35052} In contrast, plasma levels were higher in Parkinson’s disease patients with dementia than those without dementia and higher levels were correlated with deficits in memory.{35054}