Formulation: A solid
Formal Name: N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-hexadecanamide
Purity: ≥98%
Formula Markup: C34H69NO3
Formula Weight: 539,9
Shelf life (days): 1460
CAS Number: 5966-29-0
Notes: C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) (Item No. 10681) that lacks the 4,5-trans double bond.{41404} C16 dihydro Ceramide (46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome c oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome c release, or channel formation in phospholipid membranes in the absence of C16 ceramide. [Matreya, LLC. Catalog No. 2078]
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