Formulation: A solid
Formal Name: N-((2S,3R,E)-3-hydroxy-1-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadec-4-en-2-yl)hexadecanamide-d3
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C40H74D3NO8
Formula Weight: 703,1
Shelf life (days): 1460
Notes: C16 Glucosylceramide-d3 is intended for use as an internal standard for the quantification of C16 glucosylceramide by GC- or LC-MS. C16 glucosylceramide is an endogenous bioactive sphingolipid.{41488,41489} It is a precursor in the synthesis of C16 lactosylceramide (Item No. 24352) that is formed via metabolism of C16 ceramide (Item No. 10681) by glucosylceramide synthase.{41133} Inhalation of C16 glucosylceramide reduces lung colonization by P. aeruginosa and increases survival in a mouse model of cystic fibrosis.{41488} C16 Glucosylceramide levels are elevated in the plasma of Parkinson's disease patients with cognitive impairments.{41489} As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1533]
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