C18 Ceramide (d18:1/18:0), CAS 2304-81-6

Formulation: A crystalline solid

Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octadecanamide

Purity: ≥95%

Formula Markup: C36H71NO3

Formula Weight: 566

Shelf life (days): 1460

CAS Number: 2304-81-6

Notes: C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.{40029} Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells.{13918} It is selectively downregulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.{40030} [Matreya, LLC. Catalog No. 1832]

• SKU: CAY19556-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19556-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK