C18 dihydro Ceramide (d18:0/18:0), CAS 2304-80-5

Formulation: A crystalline solid

Formal Name: N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-octadecanamide

Purity: ≥98%

Formula Markup: C36H73NO3

Formula Weight: 568

Shelf life (days): 730

CAS Number: 2304-80-5

Notes: C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide (Item No. 19556) that lacks the 4,5-trans double bond.{40697} Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers α-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes.{40698} It is also elevated in the skin of patients with lesional atopic dermatitis.{40696}

• SKU: CAY24379-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24379-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK