Formulation: A solid
Formal Name: (2R)-N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy-tetracosanamide
Purity: ≥98%
Formula Markup: C42H85NO5
Formula Weight: 684,1
Shelf life (days): 1460
CAS Number: 154801-30-6
Notes: C24 (2’(R)-hydroxy) Phytoceramide is a naturally occurring sphingolipid that has been found in adlay seed hull.{48601} It inhibits LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages (IC50 = 19 μg/ml), as well as increases in COX-2 and inducible nitric oxide synthase (iNOS) levels. It increases production of chemokine (C-X-C motif) ligand 8 (CXCL8), CXCL1, chemokine (C-C motif) ligand 2 (CCL2), and CCL20 in human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner.{48602} C24 (2’(R)-hydroxy) Phytoceramide is a hydroxylated form of C24 phytoceramide (Item No. 22827). [Matreya, LLC. Catalog No. 2094]
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