Formulation: A solid
Formal Name: N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-tetracosanamide
Purity: ≥98%
Formula Markup: C42H85NO3
Formula Weight: 652,1
Shelf life (days): 730
CAS Number: 6063-36-1
Notes: C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.{37371} It is found in higher concentrations in female sebum compared to male sebum.{43449} C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.{43450} Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squamous carcinoma cells in vitro. {43451} C24 dihydro Ceramide levels are also increased in INS-1 β-cells incubated with glucose and palmitate (Item No. 10010279).{43452}