C6 L-threo Ceramide (d18:1/6:0), CAS 189894-80-2

Formulation: A solid

Formal Name: N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexanamide

Purity: ≥98%

Formula Markup: C24H47NO3

Formula Weight: 397,6

Shelf life (days): 1460

CAS Number: 189894-80-2

Notes: C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.{38646},{2814} C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).{38647} It is metabolically inactive and, unlike C6 L-erythro ceramide (Item No. 24388), C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase.{2814} C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in EL4 T cells when used at a concentration of 10 μM.{13011} [Matreya, LLC. Catalog No. 1828]

• SKU: CAY24390
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24390-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK