C8 L-threo Ceramide (d18:1/8:0), CAS 175892-44-1

Formulation: A solid

Formal Name: N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octanamide

Purity: ≥98%

Formula Markup: C26H51NO3

Formula Weight: 425,7

Shelf life (days): 1460

CAS Number: 175892-44-1

Notes: C8 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.{5258} It is cytotoxic to U937 cells (IC50 = 10 μM) and, like C8 D-threo ceramide (Item No. 24391), induces nuclear DNA fragmentation 5- to 6-fold more potently than C8 L-erythro ceramide (Item No. 62540).{38647,5258} C8 D-threo Ceramide also enhances V. cholerae cytolysin pore formation in liposome lipid membranes, as measured by calcein release, with a 50% release dose (RD50) value of ~30 μg/ml.{40652} [Matreya, LLC. Catalog No. 1830]

• SKU: CAY24392
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24392-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK