CAY10726, CAS 1611446-66-2

Formulation: A crystalline solid

Formal Name: 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-hexadecanoic acid

Purity: ≥98%

Formula Markup: C24H36ClF3N2O3

Formula Weight: 493

Shelf life (days): 730

CAS Number: 1611446-66-2

Notes: CAY10726 is an arylurea fatty acid.{40512} It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.

• SKU: CAY23859-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 23859-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK