Formulation: A crystalline solid
Formal Name: 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C19H18O8
Formula Weight: 374,3
Shelf life (days): 1460
CAS Number: 603-56-5
Notes: Chrysosplenetin is a flavonoid that has been found in A. annua and has diverse biological activities.{57215,57216,57217} It is active against P. falciparum in vitro (IC50 = 23 µM).{57215} Chrysosplenetin inhibits the cytopathic effect of enterovirus 71 (EV71) in Vero cells (EC50 = 0.68 µM) and increases survival in a neonatal mouse model of EV71 infection when administered at doses of 1 and 5 mg/kg.{57216} It also increases proliferation and osteogenic differentiation of isolated human bone marrow stromal cells (BMSCs) and prevents estrogen deficiency-induced bone loss in ovariectomized mice.{57217}
English
Deutsch
