Formulation: A crystalline solid
Formal Name: 6,9α-methylene-9β-methyl-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, monocalcium salt
Purity: ≥98%
Formula Markup: [C22H35O4]2 • Ca2+
Formula Weight: 767,1
Shelf life (days): 180
CAS Number: 81703-55-1
Notes: Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 µg/kg/min.{4373} In addition, ciprostene inhibits ADP-induced platelet aggregation ex vivo and in vitro with ID50 values of 9.1 µg/kg/min and 60 ng/ml, respectively.{4373,4375}