Formulation: A solution in ethanol
Formal Name: 6Z-hexadecenoic-8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-d19 acid
Purity: ≥99% deuterated forms (d1-d19)
Formula Markup: C16H11D19O2
Formula Weight: 273,5
Shelf life (days): 730
CAS Number: 2692623-89-3
Notes: cis-6-Hexadecenoic acid-d19 is intended for use as an internal standard for the quantification of cis-6-hexadecenoic acid (Item No. 9001845) by GC- or LC-MS. cis-6-Hexadecenoic acid is a monounsaturated fatty acid and is one of the primary fatty acids in human skin.{42782} cis-6-Hexadecenoic acid levels are increased in isolated sebum from the face and back of patients with acne.{42783} In contrast, levels are decreased in the non-lesional skin and isolated sebum of atopic dermatitis patients, which correlates with an increase in S. aureus in the sebum.{42782} It is active against S. aureus in vitro when used at a concentration of 5 µg/ml at pH 5.5.{42784} cis-6-Hexadecenoic acid disrupts membrane integrity, the proton motive force, increases membrane fluidity, and inhibits the electron transport chain in S. aureus.
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