Coumestrol, CAS 479-13-0

Formulation: A crystalline solid

Formal Name: 3,9-dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one

Purity: ≥98%

Formula Markup: C15H8O5

Formula Weight: 268,2

Shelf life (days): 1460

CAS Number: 479-13-0

Notes: Coumestrol is a phytoestrogen that occurs naturally in soybeans, spinach, and clover. It competitively (vs. 17β-estradiol, Item No. 10006315) binds the estrogen receptors ERα (IC50 = 11 nM) and ERβ (IC50 = 2 nM) and can induce ER-dependent gene expression in isolated cells.{22350,22351} Coumestrol is also a weak antagonist of pregnane X receptor (IC50 = 12 μM) as well as a potential inverse agonist of the constitutive androstane receptor (EC50 = 30 μM).{22352}

• SKU: CAY11730-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 11730-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK