Formulation: A lyophilisate
Formal Name: 2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one
Purity: ≥95%
Formula Markup: C28H37NO4
Formula Weight: 451,6
Shelf life (days): 1460
CAS Number: 53760-20-6
Notes: The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization.{21305,21310,21312,21316} This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion.{21307,21313,21306,21315} Cytochalasin J is a deacetylated analog of cytochalasin H that weakly inhibits actin assembly but significantly alters mitotic spindle microtubule organization and kinetochore structure.{25080,29674} Like cytochalasin H, cytochalasin J suppresses the production of reactive oxygen species by stimulated human neutrophils.{29673}
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