Formulation: A solid
Formal Name: (8S,9S,10R,13S,14S,17R)-13-ethyl-17-(ethynyl-13C2)-11-methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-16,16-d2-17-ol
Purity: ≥99% deuterated forms (d1-d2)
Formula Markup: C20[13C]2H28D2O
Formula Weight: 314,5
Shelf life (days): 1460
Notes: Desogestrel-13C2-d2 is intended for use as an internal standard for the quantification of desogestrel (Item No. 23651) by GC- or LC-MS. Desogestrel is a synthetic progestogen.{41180} It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine 123 (Item No. 16672) efflux, a measure of P-glycoprotein activity, ex vivo in human lymphocytes and CD8+ T cells in a dose-dependent manner.{41181} Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.
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