Formulation: A solution in ethanol (1 µg/ml each compound)
Shelf life (days): 1825
Notes: The deuterated arachidonic acid CYP450 metabolite LC-MS mixture contains deuterated versions of HETE and EET metabolites produced by the cytochrome P450 pathway of arachidonic acid metabolism. The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. This mixture is ideally suited for use as an internal standard in mass spectrometry applications. After opening, we recommend that the mixture be transferred immediately to a 1 ml glass screw cap vial, to prevent solvent evaporation, and stored at -20°C. The mixture should be discarded after multiple freeze/thaw cycles.This mixture contains deuterated forms of 20-HETE (Item No. 90030), (±)11(12)-EET (Item No. 50511), and (±)14(15)-EET (Item No. 50651), each of which have been shown to be involved in either vasoconstriction or hypertension.
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