Diacerein, CAS 13739-02-1

Formulation: A crystalline solid

Formal Name: 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid

Purity: ≥98%

Formula Markup: C19H12O8

Formula Weight: 368,3

Shelf life (days): 1460

CAS Number: 13739-02-1

Notes: Diacerein is a prodrug form of the anthraquinone derivative rhein (Item No. 17345).{65008} It inhibits RANKL- and IL-1β-induced differentiation of RAW 264.7 cells into osteoclasts when used at a concentration of 20 µg/ml.{25635} Diacerein (20 µg/ml) reduces levels of interleukin-1β-converting enzyme (ICE), also known as caspase-1, as well as IL-1β, and IL-18 in the superficial zone of human osteoarthritic cartilage explants.{65009} It decreases carrageenan-, dextran-, or zymosan-induced paw edema in rats when administered at a dose of 100 mg/kg.{65010}

• SKU: CAY11710-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 11710-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK