Formulation: A solid
Formal Name: 17,21-bis(acetyloxy)-6α,9-difluoro-11β-hydroxy-16β-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥98%
Formula Markup: C26H32F2O7
Formula Weight: 494,5
Shelf life (days): 1460
CAS Number: 33564-31-7
Notes: Diflorasone is a corticosteroid with anti-inflammatory activity.{37262} It reduces production of the inflammatory cytokines Il-6, Il-4, and macrophage inflammatory protein-2 (Mip-2) and completely inhibits swelling in the ears of toluene-2,4-diisocyaniate-sensitized mice following topical administration of 20 µL of a 0.05% solution. Diflorasone inhibits RANTES and thymus and activation regulated chemokine (TARC) in a dinitrochlorobenzene-induced mouse model of allergic contact dermatitis.{37263} It also inhibits proliferation of human keratinocytes in vitro and reduces epidermal thickening in a mouse model of psoriasis induced by imiquimod (Item No. 14956).{37264}
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