Formulation: A crystalline solid
Formal Name: 6α,9-difluoro-11β-hydroxy-16α-methyl-21-[(1-oxopentyl)oxy]-pregna-1,4-diene-3,20-dione
Purity: ≥98%
Formula Markup: C27H36F2O5
Formula Weight: 478,6
Shelf life (days): 1460
CAS Number: 59198-70-8
Notes: Diflucortolone 21-valerate is a glucocorticoid.{57467} It has anti-inflammatory effects in a rat model of croton oil-induced ear edema when applied topically (ED50 = 9.7 µg/ml).{57468} Diflucortolone 21-valerate (0.1%) also induces skin inflammation and thins the epidermis in hairless dogs following chronic topical administration and increases allergic- and non-allergic-mediated skin inflammation in mouse models of atopic dermatitis when applied topically prior to and following sensitization.{57469,57467} Formulations containing diflucortolone 21-valerate have been used in the treatment of inflammatory or allergic skin conditions.
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