Formulation: A solution in ethanol
Formal Name: 13Z,16Z,19Z-docosatrienoic acid
Purity: ≥98%
Formula Markup: C22H38O2
Formula Weight: 334,5
Shelf life (days): 730
CAS Number: 28845-86-5
Notes: Docosatrienoic acid is a rare ω-3 fatty acid not readily detected in normal phospholipid PUFA pools. It is a polyunsaturated version of the fatty acid docosanoic acid (Item No. 9000338). Docosatrienoic acid inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} It also dose-dependently inhibits the activity of mammalian DNA polymerases and human topoisomerases I and II, potentially by binding directly to the hydrophobic region of the enzymes.{39264} The cis configuration of the double bonds is important for this activity, and the carboxyl group is required as the methyl ester version has no activity at these enzymes.
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