Formulation: A solution in ethanol
Formal Name: N-(2-hydroxyethyl-1,1',2,2'-d4)-5Z,8Z,11Z,14Z,17Z-eicosapentaenamide
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C22H31D4NO2
Formula Weight: 349,5
Shelf life (days): 365
CAS Number: 946524-41-0
Notes: Eicosapentaenoyl ethanolamide (EPEA)-d4 contains four deuterium atoms at the 1, 1', 2, and 2' positions. It is intended for use as an internal standard for the quantification of EPEA by GC- or LC-mass spectrometry. Eicosapentaenoyl Ethanolamide (EPEA) is an N-acylethanolamide that inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes.{19623} Produced endogenously from eicosapentaenoic acid, EPEA serves as a metabolic signal that couples nutrient availability with growth and lifespan. EPEA also has anti-inflammatory properties, suppressing the expression of IL-6 and MCP-1 in 3T3-L1 adipocytes in response to lipopolysaccharide.{19740}