Formulation: A solution in acetonitrile
Formal Name: 9β,11β,15S-trihydroxy-(12β)-prosta-5Z,13E-dien-1-oic acid-17,17,18,18,19,19,20,20,20-d9 acid
Purity: ≥99% deuterated forms (d1-d9)
Formula Markup: C20H25D9O5
Formula Weight: 363,5
Shelf life (days): 365
Notes: ent-8-iso-15(S)-Prostaglandin F2α-d9 (ent-8-iso-15(S)-epi-PGF2α-d9) is intended for use as an internal standard for the quantification of ent-8-iso-15(S)-PGF2α (Item No. 10010380) by GC- or LC-MS. Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-PGF2α is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. {14005} This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.{14928}
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