Formulation: A solid
Formal Name: estra-1,3,5(10)-triene-3,17β-diol 17-cyclopentanepropanoate
Purity: ≥98%
Formula Markup: C26H36O3
Formula Weight: 396,6
Shelf life (days): 1460
CAS Number: 313-06-4
Notes: Estradiol cypionate is a synthetic estrogen and an ester derivative of 17β-estradiol (Item No. 10006315).{54282,54283,54284} In vivo, estradiol cypionate (0.1 mg/kg per day) reduces estrogen depletion-induced spikes in basal tail temperature in ovariectomized wild-type, estrogen receptor α knockout (ERα-/-), and ERβ-/- mice.{54282} It increases the rate of pregnancy in cows induced to ovulate small dominant follicles with gonadotropin-releasing hormone (GnRH).{54283} Estradiol cypionate also reduces edema and articular joint neutrophil infiltration in an ovariectomized mouse model of zymosan-induced arthritis.{54284} Formulations containing estradiol cypionate have been used in the treatment of menopausal symptoms and low estrogen levels.