Formulation: A crystalline solid
Formal Name: (17α)-13-ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one
Purity: ≥98%
Formula Markup: C22H28O2
Formula Weight: 324,5
Shelf life (days): 1460
CAS Number: 54048-10-1
Notes: Etonogestrel is a progesterone and androgen receptor antagonist (IC50s = 0.51 and 0.12 nM for isolated rabbit uterus and rat prostate cells, respectively) and an active metabolite of the synthetic progestogen desogestrel (Item No. 23651).{12452,53983} It increases endometrial and myometrial vascularization, uterine weight, and uterine artery length, as well as decreases the number of hormone-secreting corpus luteal glands in non-ovariectomized guinea pigs when administered subcutaneously as a 1 mm sustained-release pellet.{69282} Formulations containing etonogestrel have been used in contraceptives to prevent pregnancy.
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