Eupatorin, CAS 855-96-9

Formulation: A crystalline solid

Formal Name: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C18H16O7

Formula Weight: 344,3

Shelf life (days): 1460

CAS Number: 855-96-9

Notes: Eupatorin is a flavonoid that has been found in L. camara and has diverse biological activities.{53322,53323,53324,53325} It inhibits the growth of HeLa, MK-1, and B16/F10 tumor cells (GI50s = 15, 58, and 44 µM, respectively).{53322} Eupatorin is active against T. cruzi epimastigotes and trypomastigotes (IC50s = 0.2 and 61.8 µg/ml, respectively) without inducing cytotoxicity in Vero cells (IC50 = >500 µg/ml).{53323} It induces vasorelaxation in isolated rat thoracic aortic rings precontracted with phenylephrine (pD2 = 6.66).{53324} Eupatorin (10 and 100 µM) reduces nuclear translocation of NF-κB and STAT1α in J774 murine macrophages and reduces paw edema in a mouse model of carrageenan-induced paw inflammation when administered at a dose of 50 mg/kg.{53325}

• SKU: CAY29599-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29599-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK