Formulation: A solution in ethanol
Formal Name: 9α,11α,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid
Purity: ≥95%
Formula Markup: C23H29F3O6
Formula Weight: 458,5
Shelf life (days): 730
CAS Number: 54276-17-4
Notes: Fluprostenol is a metabolically stable analog of PGF2α with potent FP receptor agonist activity.{3160,1374} Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture. Fluprostenol inhibits PGF2α binding to human and rat FP receptors with IC50 values of 3.5 and 7.5 nM, respectively.{3160,1374} It is a much more potent luteolytic agent than PGF2α in rats with a minimum fully effective dose of 270 µg/kg to terminate pregnancy.{1182} It is also an effective inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 of 3-10 x 10−11 M.{4404}
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