Formulation: A solid
Formal Name: 1-O-[O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-6-deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide, monoammonium salt
Purity: ≥98%
Formula Markup: C79H140N3O35 • NH4 (for stearoyl)
Formula Weight: 1710
Shelf life (days): 1460
Notes: Fucosylated ganglioside GM1 is a fucose-containing glycosphingolipid that was originally found in bovine thyroid tissue.{43007} It has been found in isolated human small cell lung cancer (SCLC) tumors but is rarely found in other types of lung cancer tumors or normal tissue.{43008} Fucosylated ganglioside GM1 is shed from SCLC cells in vitro and in vivo in SCLC nude mouse xenograft models and can be detected in human plasma.{43009} It binds to cholera toxin when expressed in rat C6 glioma cultured cells, increasing intracellular cAMP to similar levels as cells expressing ganglioside GM1 (Item No. 19579).{43010} This product contains fucosylated ganglioside GM1 molecular species with primarily C22:0 and C24:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1526]
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