Formulation: A solid
Formal Name: (2R,3R)-rel-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C15H12O6
Formula Weight: 288,3
Shelf life (days): 1460
CAS Number: 20725-03-5
Notes: Fustin is a polyketide synthase-derived flavanone that has been found in R. verniciflua and has diverse biological activities.{64608,64609,64610,64611} It enhances epigallocatechin-3-O-gallate-induced decreases in the viability of U266 multiple myeloma cells when used at concentrations of 5 and 10 µM.{64609} Fustin (50 and 100 mg/kg) inhibits increases in blood glucose levels, as well as serum total cholesterol, triglyceride, and malondialdehyde (MDA) levels, in a mouse model of diabetes induced by streptozotocin (Item No. 13104).{64610} It prevents decreases in contextual- and tone fear conditioning freezing time, indicating a reversal of memory deficits, induced by amyloid-β (1-42) (Aβ42) in mice when administered at a dose of 100 mg/kg.{64611}