Formulation: A solid
Formal Name: ganglioside GM4, monoammonium salt
Purity: ≥98%
Formula Markup: C57H106N2O17 • NH3 (for 2-hydroxydocosanoyl)
Formula Weight: 1108,5
Shelf life (days): 730
Notes: Ganglioside GM4 is a sialic acid-containing glycosphingolipid found primarily in the brain of mammals, particularly in human myelin.{36629} Ganglioside GM4 is also found on epithelial cells in the intestinal tract of the red sea bream where it is an attachment site for Gram-negative Vibrios, the bacteria that causes vibriosis in humans after ingestion of raw or undercooked seafood.{36630} Ganglioside GM4 species have been found as 11 out of 61 gangliosides detected in an adrenal neuroblastoma tumor.{36631} Administration of ganglioside GM4 (80 and 160 µg) prevents development of myelin basic protein-induced experimental autoimmune encephalomyelitis (EAE) in guinea pigs.{36632} This product contains ganglioside GM4 molecular species with primarily 2-hydroxy C22:0, 2-hydroxy C24:0, and 2-hydroxy C23:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1535]
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