Formulation: A crystalline solid
Formal Name: 13-ethyl-17α-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
Purity: ≥98%
Formula Markup: C21H26O2
Formula Weight: 310,4
Shelf life (days): 1460
CAS Number: 60282-87-3
Notes: Gestodene is a progestin.{12452} It selectively binds to the progesterone receptor over the estrogen receptor.{61327} Gestodene induces transcriptional activity mediated by the progesterone receptor, and, weakly, the androgen receptor in reporter assays.{61328} It increases the growth of MCF-7 cells when used at concentrations ranging from 0.1 to 1 µM.{61329} In contrast, gestodene (0.1 mg/kg) reduces tumor growth in an estrogen-dependent model of rat mammary tumors induced by DMBA (Item No. 30383). Formulations containing gestodene, in combination with ethynyl estradiol have been used as oral contraceptives.